This page is for those who like to analyze numbers: It really helps me to see when I am getting off track and try to correct that.
The GKI (glucose ketone index) is a formula to get one number that you can plot – and see a graph of how you are doing over time.
http://www.ncbi.nlm.nih.gov/pubmed/7790697 Dr Thomas Seyfried came up with a ratio for optimal levels of glucose and ketones to fight cancer. (GKI) –
Take Glucose (measure from blood glucose test device) divided by18- it is divided by 18 to change it from mg/dL to mmol so it can be compared with the ketone which is measured in mmol
Divide your glucose by your Ketones from ketone test device. So, if I keep my blood glucose at 84 – divide that by 18 and I get 4.666 – my optimal ketone level would be 4.6 if my blood glucose is 84 on blood test.
June 8, 2015- The following article was published in March 2015
The above article has the formula to calculate a “Glucose Ketone Index” ( a ratio of blood glucose to ketones.) The Glucose Ketone Index was used to analyze results from 5 previously published reports on how effective the ketogenic diet is in suppressing cancer.
- The first study involved 2 children with brain cancer. During 8 weeks on ketogenic diet, their GKI dropped from 27.5 to .7 in one patient and 1.1 in the other patient. The children maintained that for the entire 8 weeks and had no chemotherapy. Both patients went into remission – and remained in remission up until the time of publication – which was 4 years for one and 5 years for the other.
- The second study involved a 65 year old woman with brain cancer. Her GKI went from 37.5 to 1.4 (it took 3 weeks to get there). She maintained that for 8 weeks and had no discernable brain tumor tissue at the end of 8 weeks. But she went off the diet and 10 weeks off the diet and her tumor came back.
- 3rd study was on mice- if mice had GKI of 15.2 there was rapid growth of tumor. If GKI was 3.7 the tumor decreased in size
- 4th study was on mice. Mice with GKI of 9.6-70 there was rapid growth of tumor. Mice with GKI of 1.8-4.4 had reduction in size of growth.
- 5th – mice with GKI of 32.3 survived 41 days. Mice with GKI of 5.7 plus they received radiation survived more than 200 days.
It seems that a GKI of 1 is optimal- but that is very difficult to maintain- I have not been able to keep it that low for extended periods. Blood and ketones should be measured 2-3 hours after last meal.
A normal diet has GKI around 25-35. I take my ketones and blood glucose every night before bed. I put those into an excel spreadsheet to find the average GKI for each month- and each year.
2015- average for the year was 2.41. Coconut oil or MCT oil helps raise ketones
- Jan ……… 1.9
- Feb……… 3.11
- Mar…….. 2.46
- July……. 2.65
- Aug….. 2.35
- Sept….. 2.24
- Oct…… 2.28
- Dec…… 2.24
Thoughts at end of 2015 -ketoforce helps, I quit MSG and started smoothies in Sept. Having coconut oil after every meal helps too. Main thing is that I took blood ketones almost every day
- Mar…2.25 – started Sea Cucumber Mar 15
- April… 2.2
- May…. 3.29 (not keeping track as well and assuming Sea Cucumber was enough so I could get sloppy
- Aug….2.57 – I did a bit of intermittent fasting in 2nd half month
- Sept… 2.77 kidney numbers fantastic
- Oct….2.11 – skipping breakfast seems to make this possible.
- Nov…3.48 – got flu for 4-5 days diarrhea. My cancer markers spiked by Nov 28 blood test!
Thoughts after 2016.
- In March, my cancer markers went up a bit and I started Sea Cucumber.
- I ran out of keto strips and didn’t take blood ketones as regularly- I think taking them regularly is important.
- My cancer numbers spiked when my GKI was high in Nov
- intermittent fasting seems to help keep GKI low.
- Plan for 2017- go back to measuring blood ketones more often at night. keep up the coconut oil & MCT oil and keep protein down to 2 oz per meal, keep up intermittent fasting.(skip breakfast)
- watch the GKI. If my numbers are not as good, quit the Wobenzyme and quit the AHCC. Also watch the arrowroot flour